IMMUNOSTIMULATORS
Bul Bio - National Center of Infectious and Parasitic Diseases Ltd. (BB-NCIPD Ltd.)
 
see leafletPolybacterial immunostimulator
RESPIVAX
Type: Tablets for peroral application of 25 mg (for children) and 50 mg (for adults).
Sizes: 30 tablets of 25 mg
30 tablets of 50 mg
Dose: 25 mg and 50 mg
Contents: Each tablet contains freeze-dried lysate and killed bacterial bodies of the following microbial species:
Streptococcus pneumoniae
Neisseria catarrhalis
Streptococcus pyogenes
Haemophilus influenzae
Staphylococcus aureus
Klebsiella pneumoniae
Indications: For peroral immunotherapy and immunoprophylaxis of non-specific infections of the respiratory system: acute, chronic and recurrent bronchites and tracheobronchites; acute and chronic tonsilites, pharyngites and laryngites; acute and chronic rhinites, sinuites and otites; freequently recurrent bronchopneumonias; infections of the respiratory system, accompanied with hypersensitivity to antibiotic therapy and other chimiotherapeutics; infections of the respiratory system resistant to antibiotics.
Administration: Peroral. One tablet daily according to schedule.
Storage: Between +15°C and +25°C. Protect from light. Keep in dry places.
Instruction for use: It can be used concurrently with antibiotic therapy and complex therapy of all primary and acquired immunodeficiency conditions, with malignant diseases of different localisation and in different phases of development, with different forms of syphilis.
Expiry term: 30 months
 
 
see leafletPolybacterial immunostimulator
UROSTIM
Type: Tablets for peroral application of 25 mg (for children) and 50 mg (for adults).
Sizes: 30 tablets of 25 mg
30 tablets of 50 mg
Dose: 25 mg and 50 mg
Contents: Each tablet contains freeze-dried excipient lysate and killed bacterial bodies of the following microbial species:
Escherichia coli;
Proteus mirabilis;
Klebsiella pneumoniae;
Enterococcus faecalis.
Indications: For peroral immunotherapy and immunoprophylaxis of acute recurrent or chronic non-specific infections of the urinary tract in chil ren and adults, regardless of the agent type. It is recommended for the treatment of cystites, pyelonephrites, uretrites, asymptomatic bacteriuria etc.
Administration: Peroral. One tablet daily according to schedule.
Storage: Between +15°C and +25°C.
Instruction for use: It can be used with antibiotic therapy and especially for treatment of subjects with suppressed immune reactivity obtained in result of a long antibiotic therapy.
Expiry term: 30 months
 
see leafletPolybacterial immunostimulator
DENTAVAX
Type: Tablets for peroral application of 36 mg
Size: 40 tablets of 36 mg in plastic bottle with screw cap.
Dose: 36 mg
Contents: Each tablet contains 36 mg freeze-dried killed bacterial bodies of the following microbial species:
Lactobacillus acidophilus;
Streptococcus pyogenes;
Staphylococcus aureus;
Klebsiella pneumoniae;
Candida albicans.
Indications:

For peroral immunotherapy and immunoprophylaxis in case of inflammatory and infectious diseases of the oral cavity and parodonte
- gingivitis erythematosa and ulcerosa;
- superficial or profound parodontosis;
- stomatitis, glossitis, aphtae, etc.;
- before and after tonsullectomies and after dental extractions;
-ulcerations and secondary infections caused by artificial dentures

Administration: Peroral. In case of acute inflammation - 4-6 tablets daily during 15-30 days.
In case of chronic inflammation - 3-4 tablets daily during 15-30 days.
Depending on the clinical data the treatment can be carried out 2-3 times per year.
Storage: Below +25°C.
Instruction for use: It can be used with antibiotic therapy and especially for treatment of subjects with suppressed immune reactivity obtained in result of a long antibiotic therapy.
Expiry term: 36 months
 
see leafletImmunostimulator for Cancer Immunotherapy
CALGEVAX
Type: Freeze-dried product.
Sizes: Box of 5 ampoules.
Dose: The intravesical dose consists of four ampoules suspended in 50 ml saline.
0.5 ml of the reconstituted vaccine for one scarification.
Contents: Live bacteria derived from a culture of the Bacillus of Calmette and Guerin (BCG).
Each ampoule contains 37.5 mg BCG (freeze-dried) - 1.0-3.0 x 108viable units.
Indications: In all kind of malignant tumors in which adjuvant immunotherapy is recommended, especially for bladder tumors, malignant melanoma etc.
Administration: Intraversically, percutaneously.
Storage: Between 2 °C and +8°C in a dark place. Protect from light.
Instruction for use: The vaccine should be reconstituted gently to ensure thorough mixing with the diluent. Shake the impoule until a homogenous suspension is obtained.
Intravesical use reconstitute the content of each ampoule with 1 ml of saline. Dilute the reconstituted content of the 4 ampoules in an additional 50 ml of sterile saline. Percutaneous use reconstitute the content of one ampoule with 0.5 ml of saline.
Expiry term: 24 months

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